Chemistry:2-Ethylhexyl diphenyl phosphate

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2-Ethylhexyl diphenyl phosphate
2-Ethylhexyl diphenyl phosphonate Structure.svg
Names
Preferred IUPAC name
2-Ethylhexyl diphenyl phosphate
Other names
Disflamoll DPO (Lanxess)
Phosflex 362 (ICL-IP)
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
EC Number
  • 214-987-2
KEGG
UNII
UN number 3082
Properties
C20H27O4P
Molar mass 362.406 g·mol−1
Melting point −60 °C (−76 °F; 213 K)
Boiling point 196 °C (385 °F; 469 K)
Hazards
GHS pictograms GHS09: Environmental hazard
GHS Signal word Warning
H410
P273, P391, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

2-Ethylhexyl diphenyl phosphate (Octicizer) is an organophosphate compound. It acts as both a plasticizer and flame retardant in PVC, its wide liquid range also makes it suitable as a flame retardant in hydraulic fluids. It has low acute toxicity in feeding experiments,[1] but has been implicated as a potential hormone mimetic.[2][3]

References

  1. "Toxicity of 2-ethylhexyl diphenyl phosphate. I. Immediate toxicity and effects of long-term feeding experiments". A.M.A. Archives of Industrial Hygiene and Occupational Medicine 8 (2): 170–84. August 1953. PMID 13064875. 
  2. "A review on organophosphate Ester (OPE) flame retardants and plasticizers in foodstuffs: Levels, distribution, human dietary exposure, and future directions". Environment International 127: 35–51. June 2019. doi:10.1016/j.envint.2019.03.009. PMID 30901640. 
  3. "2-Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes)". Environmental Science & Technology 54 (14): 8919–8925. July 2020. doi:10.1021/acs.est.0c02775. PMID 32559385. Bibcode2020EnST...54.8919L.