Chemistry:6-Hydroxykynurenic acid

From HandWiki
6-Hydroxykynurenic acid
6-hydroxykynurenic acid.svg
Names
Preferred IUPAC name
4,6-Dihydroxyquinoline-2-carboxylic acid
Identifiers
3D model (JSmol)
ChemSpider
Properties
C10H7NO4
Molar mass 205.169 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

6-Hydroxykynurenic acid is a constituent of ginkgo and an amino acid.[1] It is a derivative of kynurenic acid and has similarly been found to antagonize AMPA and NMDA, as well as their corresponding receptors.[2]

See also

References

  1. van Beek, Teris A (2002-08-16). "Chemical analysis of Ginkgo biloba leaves and extracts" (in en). Journal of Chromatography A. Chromatographic and Electrophoretic Analysis of Secondary Metabolites of Plants 967 (1): 21–55. doi:10.1016/S0021-9673(02)00172-3. ISSN 0021-9673. PMID 12219929. https://www.sciencedirect.com/science/article/pii/S0021967302001723. 
  2. Weber, Marco; Dietrich, Dirk; Gräsel, Ines; Reuter, Gerhard; Seifert, Gerald; Steinhäuser, Christian (2001-12-20). "6-Hydroxykynurenic acid and kynurenic acid differently antagonise AMPA and NMDA receptors in hippocampal neurones: 6-Hydroxykynurenate blocks glutamate receptors" (in en). Journal of Neurochemistry 77 (4): 1108–1115. doi:10.1046/j.1471-4159.2001.00340.x. PMID 11359876.