Chemistry:8-Bromoguanosine 3',5'-cyclic monophosphate
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Names | |
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IUPAC name
8-Bromoguanosine 3′,5′-(hydrogen phosphate)
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Preferred IUPAC name
(4aR,6R,7R,7aS)-6-(2-Amino-8-bromo-6-oxo-1,6-dihydro-9H-purin-9-yl)-2,7-dihydroxytetrahydro-2H,4H-2λ5-furo[3,2-d][1,3,2]dioxaphosphinin-2-one | |
Other names
8-Bromocyclic GMP;8-Bromo-cGMP; 8-Br-cyclic GMP; 8-Br-cGMP
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Identifiers | |
3D model (JSmol)
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Properties | |
C10H11BrN5O7P | |
Molar mass | 424.104 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Tracking categories (test):
8-Bromoguanosine 3′,5′-cyclic monophosphate is a brominated derivative of cyclic guanosine monophosphate (cGMP).[1] It acts as an activator of cGMP-dependent protein kinases.[2]
See also
- 8-Bromoadenosine 3′,5′-cyclic monophosphate (8-Br-cAMP)
References
- ↑ Rapoport, RM; Draznin, MB; Murad, F (Nov 1982). "Sodium nitroprusside-induced protein phosphorylation in intact rat aorta is mimicked by 8-bromo cyclic GMP" (Free full text). Proceedings of the National Academy of Sciences of the United States of America 79 (21): 6470–4. doi:10.1073/pnas.79.21.6470. ISSN 0027-8424. PMID 6292902. Bibcode: 1982PNAS...79.6470R.
- ↑ 8-Bromoguanosine-3′,5′-cyclic monophosphate ( 8-Br-cGMP )
Original source: https://en.wikipedia.org/wiki/8-Bromoguanosine 3',5'-cyclic monophosphate.
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