Chemistry:AGH-107
From HandWiki
Short description: Chemical compound
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| Formula | C13H12IN3 |
| Molar mass | 337.164 g·mol−1 |
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AGH-107 is a potent, selective, water-soluble and brain penetrant full agonist at the 5HT7 serotonin receptor.[1] AGH-107 is one of the few examples of low-basicity aminergic receptor agonists, which may underlie its high selectivity over the related central nervous system targets. AGH-107 was found to reverse the impairment in novel object recognition caused by MK-801 in mice. The relatively short half-life in rodents inhibited its use as a molecular probe.
See also
References
- ↑ "7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol" (in En). Scientific Reports 7 (1): 1444. May 2017. doi:10.1038/s41598-017-00822-4. PMID 28473721.
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