Chemistry:Acid fuchsin

From HandWiki
Acid fuchsin
Acid fuchsin.svg
Names
IUPAC name
Disodium 2-amino-5-[(Z)-(4-amino-3-sulfonatophenyl)(4-iminio-3-sulfonato-2,5-cyclohexadien-1-ylidene)methyl]-3-methylbenzenesulfonate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
EC Number
  • 221-816-5
UNII
Properties
C20H17N3Na2O9S3
Molar mass 585.53 g·mol−1
Hazards
GHS pictograms GHS07: Harmful
GHS Signal word Warning
H315, H319, H335
P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Acid fuchsin or fuchsine acid, (also called Acid Violet 19[1] and C.I. 42685[1]) is an acidic magenta dye with the chemical formula C20H17N3Na2O9S3. It is a sodium sulfonate derivative of fuchsine. Acid fuchsin has wide use in histology,[1] and is one of the dyes used in Masson's trichrome stain.[2] This method is commonly used to stain cytoplasm and nuclei of tissue sections in the histology laboratory in order to distinguish muscle from collagen. The muscle stains red with the acid fuchsin, and the collagen is stained green or blue with Light Green SF yellowish or methyl blue. It can also be used to identify growing bacteria.[3]

See also

References

  1. 1.0 1.1 1.2 Lillie, Ralph Dougall (1977). H. J. Conn's Biological stains (9th ed.). Baltimore: Williams & Wilkins. pp. 692. 
  2. Jocelyn H. Bruce-Gregorios, M.D.: Histopathologic Techniques, JMC Press Inc., Quezon City, Philippines, 1974. ISBN:971-11-0853-4
  3. Holman, W. L (1914). "The use of Decolorized Acid Fuchsin as an Acid Indicator in Carbohydrate Fermentation Tests with some Remarks on Acid Production by Bacteria". Journal of Infectious Diseases 15: 227–233. doi:10.1093/infdis/15.1.227. https://zenodo.org/record/2508513.