Chemistry:Bromodifluoroacetyl chloride
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Names | |
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Preferred IUPAC name
Bromodi(fluoro)acetyl chloride | |
Other names
2-Bromo-2,2-difluoroacetyl chloride
2-Bromo-2,2-difluoro-ethanoyl chloride | |
Identifiers | |
3D model (JSmol)
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Properties | |
C2BrClF2O | |
Molar mass | 193.37 g·mol−1 |
Appearance | liquid |
Boiling point | 50 °C (122 °F; 323 K) |
Hazards | |
Safety data sheet | [1] |
GHS pictograms | |
GHS Signal word | Danger |
H226, H314 | |
P210, P233, P240, P241, P242, P243, P260, P264, P280, P301+330+331, P303+361+353, P304+340, P305+351+338, P310, P321, P363, P370+378, P403+235, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Tracking categories (test):
Bromodifluoroacetyl chloride is a chemical compound with the formula BrCF2COCl. It has been used as a starting material for the synthesis of (biologically active) α,α-difluoro-γ-lactams[1] and has been used in the synthesis of trifluoromethylated C-nucleosides.[2]
See also
References
- ↑ Nagashima, H.; Isono, Y.; Iwamatsu, S. (2001). "Copper-Catalyzed Cyclization of N-Allylhalodifluoroacetamides: An Efficient Synthesis of α,α-difluoro-γ-lactams". Journal of Organic Chemistry 66 (1): 315–319. doi:10.1021/jo001187f. PMID 11429918.
- ↑ Mamata, C.; Heina, M.; Miethchen, R. (2006). "Fluorinated acyclo-C-nucleoside analogues from glycals in two steps". Carbohydrate Research 341 (10): 1758–1763. doi:10.1016/j.carres.2006.01.011. PMID 16442508.
Original source: https://en.wikipedia.org/wiki/Bromodifluoroacetyl chloride.
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