Chemistry:Bronidox

Bronidox

Names
Preferred IUPAC name 5-Bromo-5-nitro-1,3-dioxane
Other names 5-Bromo-5-nitro-m-dioxane
Identifiers
CAS Number	30007-47-7 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL3185787
ChemSpider	1741 Y
EC Number	250-001-7
PubChem CID	1807
UNII	U184I9QBNM Y
InChI InChI=1S/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2 Y Key: XVBRCOKDZVQYAY-UHFFFAOYSA-N Y InChI=1/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2 Key: XVBRCOKDZVQYAY-UHFFFAOYAG
SMILES O=[N+]([O-])C1(Br)COCOC1
Properties
Chemical formula	C4H6BrNO4
Molar mass	211.999 g·mol−1
Appearance	White crystalline powder
Melting point	60 °C (140 °F; 333 K) 58.5−62 °C
Solubility in water	insoluble
Hazards
GHS pictograms
GHS Signal word	Danger
GHS hazard statements	H302, H314, H315, H317, H410
GHS precautionary statements	P260, P261, P264, P270, P272, P273, P280, P301+312, P301+330+331, P302+352, P303+361+353, P304+340, P305+351+338, P310, P321, P330, P332+313, P333+313, P362, P363, P391, P405, P501
Lethal dose or concentration (LD, LC):
LD50 (median dose)	590 mg/kg (mouse, oral) 455 mg/kg (rat, oral) 31 mg/kg (rat, ipr.) 2500 µg (mouse, skin) 2500 µg (rat, skin)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Tracking categories (test):

• SizeSet

Bronidox, or 5-bromo-5-nitro-1,3-dioxane, is an antimicrobial chemical compound.

Bronidox causes inhibition of enzyme activity in bacteria.

Bronidox is corrosive to metals.

Uses

• Bactericide
• Fungicide, effective against yeast and other fungi
• It is used in immunology for preserving antibodies and antisera in 0.1 - 0.5% concentration. It is used as preservative to avoid use of sodium azide.
• Stabilizer
• Surfactant
• Used in cosmetics since the mid-1970s as preservative for shampoos, foam bath, etc. Maximum concentration is 0.1%.
• Some users do not recommend use in preparations destined for in vivo or tissue culture work

See also

• Bronopol