Chemistry:CYM50769
From HandWiki
CYM50769 is a drug which acts as a selective, non-peptide antagonist at the Neuropeptides B/W receptor NPBW1. It is used for fundamental research into the structure and function of the NPBW1 receptor, and has antidepressant effects in animal studies.[1][2][3]
References
- ↑ "Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7)". Bioorganic & Medicinal Chemistry Letters 22 (23): 7135–7141. December 2012. doi:10.1016/j.bmcl.2012.09.074. PMID 23079522.
- ↑ "SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists". Bioorganic & Medicinal Chemistry Letters 23 (3): 614–619. February 2013. doi:10.1016/j.bmcl.2012.12.030. PMID 23287738.
- ↑ "Npbwr1 signaling mediates fast antidepressant action". Molecular Psychiatry 30 (5): 1828–1835. May 2025. doi:10.1038/s41380-024-02790-4. PMID 39433904.
 |  |
