Chemistry:Cedramber

From HandWiki

(8α)-8-Methoxycedrane (also called Cedramber) is a fragrance compound.[1] According to International Flavors & Fragrances Inc., it has a woody, ambergris odor.[2]

Preparation

Cedryl methyl ether can be prepared from cedrol. Cedrol reacts with sodium hydride to form the sodium salt, which can be methylated by dimethyl sulfate.[3]

Safety

All endpoints were cleared in a safety assessment by the Research Institute for Fragrance Materials.[4]

References

  1. "ChemSpider". https://www.chemspider.com/Chemical-Structure.9260942.html. 
  2. "IFF". https://www.iff.com/scent/ingredients-compendium/cedramber/. 
  3. Zhu, Guangyong; Xiao, Zuobing (2022-12-28). "Flavors and Fragrances: Structure of Various Flavors with Food Ingredients". Flavors and Fragrances in Food Processing: Preparation and Characterization Methods. ACS Symposium Series. 1433. American Chemical Society. pp. 48. ISBN 9780841297319. https://doi.org/10.1021/bk-2022-1433.ch002. Retrieved 2026-04-03. 
  4. Api, A. M.; Bartlett, A.; Belsito, D.; Botelho, D.; Bruze, M.; Bryant-Friedrich, A.; Burton, G. A.; Cancellieri, M. A. et al. (2026-04-01). "RIFM fragrance ingredient safety assessment, cedryl methyl ether, CAS Registry Number 67874-81-1". Food and Chemical Toxicology. RIFM Fragrance Material Safety Assessments 210. doi:10.1016/j.fct.2026.115973. ISSN 0278-6915. https://www.sciencedirect.com/science/article/pii/S0278691526000475.