Chemistry:DMG-PEG 2000
From HandWiki
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| Names | |
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| IUPAC name
1,2-Dimyristoyl-sn-glycero-3-methoxypolyethylene glycol
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| Other names
PEG-DMG
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| Identifiers | |
3D model (JSmol)
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| Properties | |
| C 122H 242O 50 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride. It is used to manufacture lipid nanoparticles that are used in mRNA vaccines,[1] and in particular forms part of the drug delivery system for the Moderna COVID-19 vaccine.[2]
See also
- Moderna COVID-19 vaccine nanoparticle ingredients
- Distearoylphosphatidylcholine
- SM-102
- Cholesterol
References
- ↑ "Development of an Alcohol Dilution-Lyophilization Method for Preparing Lipid Nanoparticles Containing Encapsulated siRNA". Biological & Pharmaceutical Bulletin 41 (8): 1291–1294. 2018. doi:10.1248/bpb.b18-00208. PMID 30068880.
- ↑ "Moderna COVID-19 Vaccine Standing Orders for Administering Vaccine to Persons 18 Years of Age and Older". Centers for Disease Control and Prevention (CDC). https://www.cdc.gov/vaccines/covid-19/info-by-product/moderna/downloads/standing-orders.pdf.
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