Chemistry:Esproquin

From HandWiki
Short description: Tetrahydroisoquinoline-derivative molecule
Esproquin
Esproquin.svg
Clinical data
Other namesEsproquine
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC14H21NOS
Molar mass251.39 g·mol−1
3D model (JSmol)

Esproquin is an α2-adrenergic receptor agonist derived from tetrahydroisoquinoline.[1] It has a positive inotropic effect, suggesting potential use in treatment of chronic heart failure.[2]

References

  1. "Preparation and cardiovascular actions of a group of tetrahydroisoquinoline derivatives". Journal of Medicinal Chemistry 16 (7): 859–61. July 1973. doi:10.1021/jm00265a028. PMID 4146907. 
  2. "Positive inotropic effect of oral esproquin in normal subjects". Clinical Pharmacology and Therapeutics 14 (3): 427–33. 1973. doi:10.1002/cpt1973143427. PMID 4698571.