Chemistry:Glucametacin

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Short description: NSAID analgesic and anti-inflammatory drug
Glucametacin
Glucametacin.svg
Clinical data
Trade namesTeoremac
Other namesIndometacin glucosamide
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC25H27ClN2O8
Molar mass518.95 g·mol−1

Glucametacin is a non-steroidal anti-inflammatory drug used for the treatment of mild or moderate pain associated with rheumatoid arthritis, osteoarthritis, and other rheumatological disorders.[1] It has analgesic and anti-inflammatory effects.[1][2][3]

Glucametacin is an amide of indometacin with glucosamine.

References

  1. 1.0 1.1 "Further studies on glucametacin in rheumatoid arthritis and in other chronic types of rheumatism". Current Medical Research and Opinion 7 (4): 227–233. 1981. doi:10.1185/03007998109114267. PMID 6971729. 
  2. "Comparative effects of non-steroidal anti-inflammatory drugs, mefenamic acid, metiazinic acid and glucametacin on the inflammatory response induced by subcutaneous implantation of human dental plaque and on the mitotic activity of isoproterenol-stimulated parotid glands of rats". Cellular and Molecular Biology 32 (5): 619–626. 1986. PMID 3779763. 
  3. "Double-blind comparison of glucametacin and ketoprofen in chronic arthropathies". Current Medical Research and Opinion 8 (5): 321–326. 1983. doi:10.1185/03007998309112391. PMID 6340973.