Chemistry:Imiclopazine
From HandWiki
Short description: Antipsychotic medication
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| Trade names | Ponsital[1][2] |
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| Formula | C25H32ClN5OS |
| Molar mass | 486.08 g·mol−1 |
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Imiclopazine is an antipsychotic drug of the phenothiazines class, developed in the 1960s by the pharmaceutical company Asta-Werke under the brand name Ponsital. It demonstrated strong sedative and antiemetic properties.[3][4]
It was initially researched for the treatment of schizophrenia and had favorable clinical trials,[5] but ultimately was never brought to market.[3]
References
- ↑ (in en) Drugs: Synonyms and Properties (2nd ed.). John Wiley & Sons. 2002-02-01. pp. 427. ISBN 978-0-566-08491-1. https://books.google.com/books?id=QxcoEAAAQBAJ&pg=PA427.
- ↑ "Substâncias e remédios sob controle" (in pt-br). Jornal do Brasil: pp. 14. 1986-11-05. https://memoria.bn.br/pdf/030015/per030015_1986_00211.pdf.
- ↑ 3.0 3.1 "Imiclopazine" (in en). NCATS Inxight Drugs. National Center for Advancing Translational Sciences (NCATS). https://drugs.ncats.io/drug/WGL8B3MDAS.
- ↑ "[Treatment of schizophrenia with imiclopazine, pimozide, imagotan and trifluorperidol. Comparative study]". Psychiatria Polska 7 (1): 57–63. 1973. PMID 4146043.
- ↑ "Langzeitbehandlung mit PONSITAL bei chronisch psychisch Kranken" (in de). International Pharmacopsychiatry 1 (1): 80–85. 1968. doi:10.1159/000467919. ISSN 0020-8272. https://www.karger.com/Article/FullText/467919.
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