Chemistry:Lactucin

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Lactucin
Lactucin.png
Names
Preferred IUPAC name
(3aR,4S,9aS,9bR)-4-Hydroxy-9-(hydroxymethyl)-6-methyl-3-methylidene-3,3a,4,5,9a,9b-hexahydroazuleno[4,5-b]furan-2,7-dione
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
KEGG
UNII
Properties
C15H16O5
Molar mass 276.28 g/mol
Appearance White crystalline solid
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Lactucin is a bitter substance that forms a white crystalline solid and belongs to the group of sesquiterpene lactones. It is found in some varieties of lettuce and is an ingredient of lactucarium. It has been shown to have analgesic and sedative properties.[1] It has also shown some antimalarial effects.[2] It is also found in dandelion coffee.

It acts as an adenosine receptor agonist.[3][better source needed]

See also

References

  1. "Analgesic and Sedative Activities of Lactucin and some Lactucin-Like Guaianolides in Mice". Journal of Ethnopharmacology 107 (2): 254–258. 2006. doi:10.1016/j.jep.2006.03.003. PMID 16621374. 
  2. "Antimalarial Activity of Lactucin and Lactucopicrin: Sesquiterpene Lactones Isolated from Cichorium intybus L.". Journal of Ethnopharmacology 95 (2–3): 455–457. 2004. doi:10.1016/j.jep.2004.06.031. PMID 15507374. 
  3. Qasem, Jamal R (2015-04-01). "Prospects of wild medicinal and industrial plants of saline habitats in the Jordan Valley". Pakistan Journal of Botany 47 (2). ISSN 0556-3321. https://www.researchgate.net/publication/275339308.