Chemistry:Lenampicillin

From HandWiki
Short description: Chemical compound
Lenampicillin
Lenampicillin.svg
Clinical data
Trade namesTakacillin, Varacillin
Other namesKBT-1585
Legal status
Legal status
  • Rx in Japan
Identifiers
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC21H23N3O7S
Molar mass461.49 g·mol−1

Lenampicillin is an antibiotic drug of the penicillin class. It is a produg of ampicillin; after oral administration of lenampicillin, ampicillin is rapidly formed.[1]

Lenampicillin inhibits bacterial penicillin binding proteins (transpeptidase) and is effective against a wide range of bacterial infections.[2]

Lenampicillin was developed in Japan and has been marketed there.[2]

References

  1. Saito, A.; Nakashima, M. (1986). "Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers". Antimicrobial Agents and Chemotherapy 29 (5): 948–950. doi:10.1128/aac.29.5.948. PMID 3729355. 
  2. 2.0 2.1 "Lenampicillin". InxightDrugs. National Center for Advancing Translational Sciences. https://drugs.ncats.io/drug/8M568DM08K.