Chemistry:NNZ-2591

From HandWiki
Short description: Chemical compound
NNZ-2591
NNZ-2591.svg
Clinical data
Other namesCyclo(L-glycyl-L-2-allylproline)
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC10H14N2O2
Molar mass194.234 g·mol−1
3D model (JSmol)

NNZ-2591 is a synthetic analog of cyclic glycine-proline and experimental drug developed for Angelman syndrome, Phelan-McDermid syndrome, Pitt Hopkins syndrome,[1][2] and Prader-Willi syndrome.[3]

References

  1. Markati, Theodora; Duis, Jessica; Servais, Laurent (3 July 2021). "Therapies in preclinical and clinical development for Angelman syndrome". Expert Opinion on Investigational Drugs 30 (7): 709–720. doi:10.1080/13543784.2021.1939674. 
  2. Heussler, Helen S. (March 2021). "Emerging Therapies and challenges for individuals with Angelman syndrome". Current Opinion in Psychiatry 34 (2): 123–128. doi:10.1097/YCO.0000000000000674. ISSN 0951-7367. https://journals.lww.com/co-psychiatry/abstract/2021/03000/emerging_therapies_and_challenges_for_individuals.9.aspx. 
  3. "An Open-Label Study of Oral NNZ-2591 in Prader-Willi Syndrome (PWS-001) (PWS-001) NCT05879614". https://clinicaltrials.gov/study/NCT05879614.