Chemistry:Proroxan
From HandWiki
Short description: Antihypertensive drug
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| Other names | Pyrroxane, Pirroksan |
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| Formula | C21H23NO3 |
| Molar mass | 337.419 g·mol−1 |
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Proroxan (INN; also known as pyrroxane and pirroksan) is a pharmaceutical drug used as an antihypertensive and in the treatment of Ménière’s disease, motion sickness, and allergic dermatitis.[1][2]
Proroxan is a non-selective alpha-blocker (α-adrenoreceptor antagonist).[1]
Proroxan was developed in the 1970s at the Institute of Toxicology of the USSR Ministry of Health[3] and today is primarily used in Russia. Though originally developed as an antihypertensive, its use can lead to a decrease in alcohol and drug consumption. Currently proroxan is used almost exclusively in psychiatry, narcology, and neurology.[3]
References
- ↑ 1.0 1.1 "Proroxan hydrochloride". Inxight Drugs. National Institutes of Health. https://drugs.ncats.io/drug/694Z9P44G4.
- ↑ "ПРОРОКСАН (PROROXAN) ОПИСАНИЕ". https://www.vidal.ru/drugs/molecule/893.
- ↑ 3.0 3.1 "Clinical pharmacology of pyrroxane (proroxane)" (in RU). Reviews on Clinical Pharmacology and Drug Therapy 18 (4): 335–350. 2020. doi:10.17816/RCF184335-350. https://journals.eco-vector.com/RCF/article/view/56961.
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