Chemistry:SCH 900271

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SCH 900271
SCH 900271.svg
Names
Preferred IUPAC name
5-[3-(1-Methylcyclopropyl)propyl]-2H-pyrano[2,3-d]pyrimidine-2,4,7(1H,3H)-trione
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
DrugBank
UNII
Properties
C14H16N2O4
Molar mass 276.292 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

SCH 900271 is a nicotinic acid derivative designed to treat dyslipidemia. It reduced plasma free fatty acids levels, but without significant flushing, a side effect common with niacin that limits its usefulness. SCH 900271 is currently in human trials.[1]

References

  1. Palani, Anandan (November 2011). "Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia". ACS Medicinal Chemistry Letters 3 (1): 63–8. doi:10.1021/ml200243g. PMID 24900372.