Chemistry:Suntinorexton

Suntinorexton
Identifiers
	IUPAC name N-[(2S,3S)-2-[[2-fluoro-3-(3-fluorophenyl)phenyl]methyl]-1-(2-hydroxy-2-methylpropanoyl)pyrrolidin-3-yl]ethanesulfonamide;
CAS Number	2274802-89-8 ;
PubChem CID	137460941;
UNII	FF2NQ35DA4;
Chemical and physical data
Formula	C23H28F2N2O4S
Molar mass	466.54 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCS(=O)(=O)N[C@H]1CCN([C@H]1CC2=C(C(=CC=C2)C3=CC(=CC=C3)F)F)C(=O)C(C)(C)O;
	InChI InChI=1S/C23H28F2N2O4S/c1-4-32(30,31)26-19-11-12-27(22(28)23(2,3)29)20(19)14-16-8-6-10-18(21(16)25)15-7-5-9-17(24)13-15/h5-10,13,19-20,26,29H,4,11-12,14H2,1-3H3/t19-,20-/m0/s1; Key:MQDUVMBBJZLFHF-PMACEKPBSA-N;

Short description: Chemical compound

Suntinorexton (INN) is an experimental orexin receptor agonist.^[1] It acts as a selective agonist of the orexin OX₂ receptor and was described in 2019 in a patent by Takeda Pharmaceutical Company.^[2]

References

↑ "International Nonproprietary Names for Pharmaceutical Substances (INN)". WHO Drug Information 34 (1): 93–269. 2020. https://www.who.int/medicines/publications/druginformation/issues/INN_List-123.pdf. "Proposed INN: List 123".
↑ Kajita Y, Mikami S, Miyanohana Y, Koike T, Daini M, Oyabu N, Ogino M, Takeuchi K, Ito Y, Tokunaga N, Sugimoto T, Miyazaki T, Oda T, Hoashi Y, Hattori Y, Imamura K, "Heterocyclic compound and use therof", WO patent application 2019027058, published 2019-02-07, assigned to Takeda Pharmaceutical Company.

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Identifiers

IUPAC name N-[(2S,3S)-2-[[2-fluoro-3-(3-fluorophenyl)phenyl]methyl]-1-(2-hydroxy-2-methylpropanoyl)pyrrolidin-3-yl]ethanesulfonamide
CAS Number	2274802-89-8^Y
PubChem CID	137460941
UNII	FF2NQ35DA4
Chemical and physical data
Formula	C₂₃H₂₈F₂N₂O₄S
Molar mass	466.54 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCS(=O)(=O)N[C@H]1CCN([C@H]1CC2=C(C(=CC=C2)C3=CC(=CC=C3)F)F)C(=O)C(C)(C)O
InChI InChI=1S/C23H28F2N2O4S/c1-4-32(30,31)26-19-11-12-27(22(28)23(2,3)29)20(19)14-16-8-6-10-18(21(16)25)15-7-5-9-17(24)13-15/h5-10,13,19-20,26,29H,4,11-12,14H2,1-3H3/t19-,20-/m0/s1 Key:MQDUVMBBJZLFHF-PMACEKPBSA-N