Chemistry:Thioformamide
From HandWiki
Thioformamide is the organosulfur compound with the formula HC(S)NH2. Although lightly studied, it is of interest as the parent thioamide. The structure has been confirmed by X-ray crystallography, which reveals the expected planar structure with a C=S bond (167 picometer).[1]
The compound is prepared by treating formamide with phosphorus pentasulfide.[1]
As a component of the cyanosulfidic protometabolism hypothesis, thioformamide and related compounds have been implicated as prebiotic precursors to peptides.[2]
References
- ↑ 1.0 1.1 Bernhardt, Bastian; Dressler, Friedemann; Eckhardt, André K.; Becker, Jonathan; Schreiner, Peter R. (2021). "Characterization of the Simplest Thiolimine: The Higher Energy Tautomer of Thioformamide". Chemistry – A European Journal 27 (22): 6732–6739. doi:10.1002/chem.202005188. PMID 33496350. Bibcode: 2021ChEuJ..27.6732B.
- ↑ Patel, Bhavesh H.; Percivalle, Claudia; Ritson, Dougal J.; Duffy, Colm D.; Sutherland, John D. (2015). "Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism". Nature Chemistry 7 (4): 301–307. doi:10.1038/nchem.2202. PMID 25803468. Bibcode: 2015NatCh...7..301P.
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