Chemistry:Trimethyltin acetate
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| Names | |
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| IUPAC name
Trimethylstannyl acetate[1]
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| Other names | |
| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| CH 3COOSn(CH 3) 3 | |
| Molar mass | 222.859 g·mol−1 |
| Appearance | White crystalline solid |
| Melting point | 193 °C (379 °F; 466 K)[2] |
| Solubility | Sparingly soluble in chloroform and carbon tetrachloride. |
| Hazards | |
| Main hazards | Highly toxic |
| GHS pictograms | 
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| GHS Signal word | Danger |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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9 mg/kg (rat, oral) |
| Related compounds | |
Related compounds
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Trimethyltin acetate is an organotin compound with the chemical formula CH
3COOSn(CH
3)
3. It is a white crystalline solid. It is a poison.
Preparation
Trimethyltin acetate can be prepared by reaction between tetramethyltin and mercury(I) acetate in methanol at room temperature.[3]
The previously known insoluble trimethyltin acetate has been converted to a new, soluble form by heating in a sealed tube with cyclohexane at 100 °C. The effects of temperature, concentration, and added complexing agents on the infrared and NMR spectra are reported. The results show an equilibrium in solution between monomeric and polymeric forms. It is suggested that the polymeric forms may have a cyclic structure, in contrast to the infinite linear polymeric structure attributed to the insoluble form.[4]
Uses
Trimethyltin acetate shows low antifungal activity.[5]
Safety
Triorganyltin compounds, like trimethyltin acetate, are poisonous. They are highly toxic if swallowed and harmful in contact with skin. Cause serious skin and eye irritation. They can cause serious eye damage. Cause serious damages to organs and nerves. They are highly toxic to aquatic life, with long-lasting effects.[6][7]
References
- ↑ 1.0 1.1 1.2 1.3 "Trimethyltin acetate". https://pubchem.ncbi.nlm.nih.gov/compound/Trimethyltin-acetate.
- ↑ "CAS Common Chemistry". https://commonchemistry.cas.org/detail?cas_rn=1118-14-5.
- ↑ Plazzogna, Gualtiero; Peruzzo, Valerio; Tagliavini, Giuseppe (1969). "A new method of preparing a soluble form of trimethyltin acetate". Journal of Organometallic Chemistry 16 (3): 500–502. doi:10.1016/S0022-328X(00)89777-6. https://linkinghub.elsevier.com/retrieve/pii/S0022328X00897776. Retrieved 2026-01-05.
- ↑ Simons, Paul B.; Graham, W. A. G. (June 1, 1967). "Studies of organotin chemistry: I. Preparation and properties of new, soluble forms of trimethyltin formate and acetate". Journal of Organometallic Chemistry 8 (3): 479–490. doi:10.1016/S0022-328X(00)83669-4. ISSN 0022-328X. https://www.sciencedirect.com/science/article/pii/S0022328X00836694.
- ↑ van der Kerk, G. J. M.; Luijten, J. G. A. (1956). "Investigations on organo-tin compounds. V The preparation and antifungal properties of unsymmetrical tri-n-alkyltin acetates" (in en). Journal of Applied Chemistry 6 (2): 56–60. doi:10.1002/jctb.5010060202. ISSN 1934-998X. https://onlinelibrary.wiley.com/doi/abs/10.1002/jctb.5010060202.
- ↑ "DETOX Program Fact Sheet – Organotin Compounds". https://www.rewe-group.com/content/uploads/2020/12/FS-Organotin-Compounds.pdf.
- ↑ Barbosa, Carolina Monteiro de Lemos; Ferrão, Fernanda Magalhães; Graceli, Jones B. (2018). "Organotin Compounds Toxicity: Focus on Kidney". Frontiers in Endocrinology 9. doi:10.3389/fendo.2018.00256. PMID 29872423.
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