Medicine:Periorbital dark circles
| Periorbital dark circles | |
|---|---|
| Other names | Dark circles, infraorbital venous stasis, periorbital hyperpigmentation |
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| Minor dark circles and a hint of periorbital puffiness—a combination principally suggestive of minor sleep deprivation. | |
| Specialty | Sleep medicine |
Periorbital dark circles are dark blemishes around the eyes. There are many causes of this symptom, including heredity and bruising.[1]
Causes
Anatomical factors
Bony structure and prominence of the orbicularis oculi muscle can contribute to infraorbital dark circles.[2][3] Skin in the lower eyelid is very thin which accentuates subdermal features.[2]
Allergies, asthma, and eczema
Any condition that causes the eyes to itch can contribute to darker circles due to rubbing or scratching the skin around them. Hay fever sufferers in particular will notice under-eye "smudges" during the height of the allergy season. Atopy can lead to frequent rubbing of the eyes, leading to local inflammation and increased pigmentation.[4]
Also, dark circles from allergies are caused by superficial venous congestion[5] in the capillaries under the eyes.
Medications
Any medications that cause blood vessels to dilate can cause circles under the eyes to darken. The skin under the eyes is very delicate, any increased blood flow shows through the skin.
Cortisol deficiency
When cortisol is deficient the pituitary compensates by producing excess adrenocorticotropic hormone (ACTH) and melanocyte-stimulating hormone (MSH), the latter resulting in dark circles under the eyes.[6]
Anemia
The lack of nutrients in the diet, or the lack of a balanced diet, can contribute to the discoloration of the area under the eyes. It is believed that iron deficiency and vitamin B12 deficiency can cause dark circles as well.[7] Iron deficiency is the most common type of anemia and this condition is a sign that not enough oxygen is getting to the body tissues.
The skin can also become more pale during pregnancy and menstruation (due to lack of iron), allowing the underlying veins under the eyes to become more visible.
Fatigue
A lack of sleep and mental fatigue can cause paleness of the skin, allowing the blood underneath the skin to become more visible and appear bluer or darker.[8][better source needed]
Age
Dark circles are likely to become more noticeable and permanent with age. This is because as people get older, their skin loses collagen, becoming thinner and more translucent. As facial fat descends and fat volume decreases, the somewhat inflexible ligaments can result in orbital rim and facial hollowing.[2] Photoaging has similar effects. [3] Hemoglobin breakdown products such as hemosiderin and biliverdin can leak from the vascular contributing to pigmentation changes.[2]
Circles may also gradually begin to appear darker in one eye than the other as a result of some habitual facial expressions, such as an uneven smile.[citation needed]
Sun exposure
Prompts your body to produce more melanin, the pigment that gives skin its color.[tone][9]
Periorbital hyperpigmentation
Periorbital hyperpigmentation is the official name for when there is more melanin produced around the eyes than is usual, giving them a darker color.[10]
Treatment
At one time, hydroquinone solution was often mixed in an oil-free moisturizer that acted like a skin bleach. However the use of hydroquinone for skin whitening has been banned in European countries due to health concerns. In 2006, the United States Food and Drug Administration revoked its approval of hydroquinone for over the counter preparations warning that it may cause cancer or have many other detrimental effects. [citation needed]
The use of hydroquinone skin-whitening products can be toxic, harmful or lethal for humans. [citation needed]
Modern treatments include topical creams that are marketed for the condition. Various ingredients have been researched, developed and included in these creams. For example, recently, chemical compounds called alpha hydroxy acids (AHAs) have been added as a beneficial ingredient to creams for dark circles.[11] Specialist treatments including laser and intense pulsed light skin surgery can also be used.[12] Low-level laser therapy, autologous fat transplantation and hyaluronic acid fillers are also alternative treatment options.[13]
In addition, many skin care ingredients can help in the form of eye creams. Caffeine is a potent vasoconstrictor that has been proven to improve the look of dark circles[14] by constricting, or tightening, the dilated vessels under eyes. Vitamin C can help brighten hyperpigmentation as well as thicken the dermal layer of skin which conceals dark circles.[15]
See also
References
- ↑ "What causes the dark circles that sometimes appear under my eyes?". Mayo Clinic Women's Healthsource 7 (6): 8. 2003. PMID 12838159.
- ↑ 2.0 2.1 2.2 2.3 "Infraorbital Dark Circles: A Review of the Pathogenesis, Evaluation and Treatment". Journal of Cutaneous and Aesthetic Surgery 9 (2): 65–72. 2016. doi:10.4103/0974-2077.184046. PMID 27398005.
- ↑ 3.0 3.1 "Dark circles: etiology and management options". Clinics in Plastic Surgery 42 (1): 33–50. 2015. doi:10.1016/j.cps.2014.08.007. PMID 25440739.
- ↑ "Study of Causative Factors and Clinical Patterns of Periorbital Pigmentation". Indian Dermatology Online Journal 10 (3): 293–295. 2019. doi:10.4103/idoj.IDOJ_158_18. PMID 31149574.
- ↑ Murdoch, Marshall (2016-11-02). "Dark circles in the periorbital region: diagnosis and treatment options". Journal of Aesthetic Nursing 5 (9): 431–435. doi:10.12968/joan.2016.5.9.431. ISSN 2050-3717. https://www.magonlinelibrary.com/doi/abs/10.12968/joan.2016.5.9.431.
- ↑ "Melanin pigmentation in mammalian skin and its hormonal regulation". Physiological Reviews 84 (4): 1155–1228. 2004. doi:10.1152/physrev.00044.2003. PMID 15383650.
- ↑ "Why Do I Have Dark Circles Under My Eyes". https://www.superpharmacy.com.au/blog/why-do-i-have-dark-circles-under-my-eyes.
- ↑ "Dark Circles Under the Eyes". 2012-06-03. http://www.medicinenet.com/dark_circles_under_the_eyes/symptoms.htm.
- ↑ "Dark circles under eyes Causes" (in en). https://www.mayoclinic.org/symptoms/dark-circles-under-eyes/basics/definition/sym-20050624.
- ↑ Mac-Mary, Sophie; Zornoza Solinis, Itziar; Predine, Océane; Sainthillier, Jean-Marie; Sladen, Christelle; Bell, Mike; O’Mahony, Mark (2019-12-18). "Identification Of Three Key Factors Contributing To The Aetiology Of Dark Circles By Clinical And Instrumental Assessments Of The Infraorbital Region". Clinical, Cosmetic and Investigational Dermatology 12: 919–929. doi:10.2147/CCID.S217956. ISSN 1178-7015. PMID 31908515.
- ↑ "Alpha Hydroxy Acids". http://www.cosmeticsinfo.org/alpha-hydroxy-acids.
- ↑ "Undereye Circles". http://www.docshop.com/education/dermatology/skin-flaws/undereye-circles.
- ↑ Alsaad, SM; Mikhail, M (February 2013). "Periocular hyperpigmentation: a review of etiology and current treatment options.". Journal of Drugs in Dermatology 12 (2): 154–7. PMID 23377386.
- ↑ Ohshima, Hiroshi; Mizukoshi, Koji; Oyobikawa, Midori; Matsumoto, Katsuo; Takiwaki, Hirotsugu; Kanto, Hiromi; Itoh, Masatoshi (2009). "Effects of vitamin C on dark circles of the lower eyelids: quantitative evaluation using image analysis and echogram" (in en). Skin Research and Technology 15 (2): 214–217. doi:10.1111/j.1600-0846.2009.00356.x. ISSN 1600-0846. PMID 19626722. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0846.2009.00356.x.
- ↑ Ohshima, Hiroshi; Mizukoshi, Koji; Oyobikawa, Midori; Matsumoto, Katsuo; Takiwaki, Hirotsugu; Kanto, Hiromi; Itoh, Masatoshi (2009). "Effects of vitamin C on dark circles of the lower eyelids: quantitative evaluation using image analysis and echogram" (in en). Skin Research and Technology 15 (2): 214–217. doi:10.1111/j.1600-0846.2009.00356.x. ISSN 1600-0846. PMID 19626722. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0846.2009.00356.x.
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