Chemistry:Pyrrole-2-carboxylic acid

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Pyrrole-2-carboxylic acid
Pyrrole-2-CO2H.svg
Names
Other names
2-Mialine, 2-Minaline, Minalin, Minaline
Identifiers
3D model (JSmol)
80825
ChEBI
ChEMBL
ChemSpider
DrugBank
EC Number
  • 211-221-9
101562
KEGG
Properties
C5H5NO2
Molar mass 111.100 g·mol−1
Appearance white solid
Melting point 206 °C (403 °F; 479 K)
Hazards
GHS pictograms GHS07: Harmful
GHS Signal word Warning
H315, H319, H335
P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Pyrrole-2-carboxylic acid is an organic compound with the formula HNC4H3CO2H. It is one of two monocarboxylic acids of pyrrole. It is a white solid. It arises in nature by dehydrogenation of the amino acid proline.[1] It also arises by carboxylation of pyrrole.[2] The ethyl ester of this acid is readily prepared from pyrrole.[3]

References

  1. Thomas, Michael G.; Burkart, Michael D.; Walsh, Christopher T. (2002). "Conversion of L-Proline to Pyrrolyl-2-Carboxyl-S-PCP during Undecylprodigiosin and Pyoluteorin Biosynthesis". Chemistry & Biology 9 (2): 171–184. doi:10.1016/S1074-5521(02)00100-X. PMID 11880032. 
  2. Wieser, Marco; Yoshida, Toyokazu; Nagasawa, Toru (2001). "Carbon dioxide fixation by reversible pyrrole-2-carboxylate decarboxylase and its application". Journal of Molecular Catalysis B: Enzymatic 11 (4–6): 179–184. doi:10.1016/S1381-1177(00)00038-2. 
  3. Denis M. Bailey, Robert E. Johnson, and Noel F. Albertson (1971). "Ethyl Pyrrole-2-Carboxylate". Organic Syntheses 51: 100. doi:10.15227/orgsyn.051.0100.