Biology:SRD5A3
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Steroid 5-alpha-reductase 3, also known as 3-oxo-5-alpha-steroid 4-dehydrogenase 3, is an enzyme that in humans is encoded by the SRD5A3 gene.[1][2] It is one of three forms of 5α-reductase.
See also
- SRD5A3-CDG
- Congenital disorder of glycosylation
- Kahrizi syndrome, a syndrome caused by a mutation in this gene
References
- ↑ "Entrez Gene: steroid 5 alpha-reductase 3". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79644.
- ↑ "Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer". Cancer Sci. 99 (1): 81–6. January 2008. doi:10.1111/j.1349-7006.2007.00656.x. PMID 17986282.
Further reading
- "Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones.". Endocr. Rev. 25 (6): 947–70. 2004. doi:10.1210/er.2003-0030. PMID 15583024.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2002. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder.". Cell 142 (2): 203–17. 2010. doi:10.1016/j.cell.2010.06.001. PMID 20637498.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
 |  |
