Biology:Biliverdin reductase A
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
| biliverdin reductase A | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Biliverdin reductase A dimer, Human | |||||||||
| Identifiers | |||||||||
| EC number | 1.3.1.24 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
 Generic protein structure example |
Biliverdin reductase A is a protein that in humans is encoded by the BLVRA gene.[1][2]
Function
The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH.[1]
Clinical significance
Mutations in this gene are associated with hyperbiliverdinemia.[1]
References
- ↑ 1.0 1.1 1.2 "Entrez Gene: Biliverdin reductase A". https://www.ncbi.nlm.nih.gov/gene/644.
- ↑ Class 1 Oxidoreductases V. Springer Handbook of Enzymes. 21 (2nd ed.). Springer Science & Business Media. 2004. pp. 140–. ISBN 978-3-540-22515-7.
External links
- Human BLVRA genome location and BLVRA gene details page in the UCSC Genome Browser.
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Biliverdin reductase A
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
 |  |
