Chemistry:Verosudil

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Short description: Chemical compound
Verosudil
Verosudil structure.png
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC17H17N3O2S
Molar mass327.40 g·mol−1
3D model (JSmol)

Verosudil (AR-12286) is a drug which acts as a potent and selective inhibitor of the enzyme Rho kinase, and has been investigated for the treatment of glaucoma.[1][2]

See also

References

  1. "Ocular hypotensive effect of the Rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension". American Journal of Ophthalmology 152 (5): 834–41.e1. November 2011. doi:10.1016/j.ajo.2011.04.012. PMID 21794845. 
  2. "Efficacy of Topically Administered Rho-Kinase Inhibitor AR-12286 in Patients With Exfoliation Syndrome and Ocular Hypertension or Glaucoma". Journal of Glaucoma 25 (9): e807-14. September 2016. doi:10.1097/IJG.0000000000000508. PMID 27552517.