Biology:Casbene synthase

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casbene synthase
Identifiers
EC number4.2.3.8
CAS number69106-45-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The enzyme casbene synthase (EC 4.2.3.8) catalyzes the chemical reaction

geranylgeranyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] casbene + diphosphate

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming). Other names in common use include casbene synthetase, and geranylgeranyl-diphosphate diphosphate-lyase (cyclizing). This enzyme participates in diterpenoid biosynthesis.

References

  • "Casbene synthetase: regulation of phytoalexin biosynthesis in Ricinus communis L. seedlings. Purification of casbene synthetase and regulation of its biosynthesis during elicitation". Arch. Biochem. Biophys. 238 (1): 325–33. 1985. doi:10.1016/0003-9861(85)90171-7. PMID 3985625.