Biology:12-hydroxydihydrochelirubine 12-O-methyltransferase
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Short description: Class of enzymes
| 12-hydroxydihydrochelirubine 12-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.120 | ||||||||
| CAS number | 158736-40-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a 12-hydroxydihydrochelirubine 12-O-methyltransferase (EC 2.1.1.120) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + dihydromacarpine
Thus, the two substrates of this enzyme are S-adenosyl methionine and 12-hydroxydihydrochelirubine, whereas its two products are S-adenosylhomocysteine and dihydromacarpine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.
References
- "Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine in dihydromacarpine formation by Thalictrum bulgaricum". Phytochemistry 36 (6): 1409–1416. 1994. doi:10.1016/S0031-9422(00)89732-0.
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