Biology:Sym-norspermidine synthase
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Short description: Class of enzymes
| sym-norspermidine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.23 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a sym-norspermidine synthase (EC 2.5.1.23) is an enzyme that catalyzes the chemical reaction
- S-adenosylmethioninamine + propane-1,3-diamine [math]\displaystyle{ \rightleftharpoons }[/math] 5'-methylthioadenosine + bis(3-aminopropyl)amine
Thus, the two substrates of this enzyme are S-adenosylmethioninamine and propane-1,3-diamine, whereas its two products are 5'-methylthioadenosine and bis(3-aminopropyl)amine.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase. This enzyme participates in urea cycle and metabolism of amino groups.
References
- "Studies on polyamine biosynthesis in Euglena gracilis". Biochim. Biophys. Acta 565 (1): 199–207. 1979. doi:10.1016/0005-2787(79)90096-0. PMID 116684.
- "Biosynthesis of polyamines in Euglena gracilis". Phytochemistry 19 (5): 787–790. 1980. doi:10.1016/0031-9422(80)85111-9.
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