Biology:All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific)
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Short description: Class of enzymes
| All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.84 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) (EC 2.5.1.84, nonaprenyl diphosphate synthase, solanesyl diphosphate synthase, SolPP synthase, SPP-synthase, SPP synthase, solanesyl-diphosphate synthase, OsSPS2) is an enzyme with systematic name geranyl-diphosphate:isopentenyl-diphosphate transtransferase (adding 7 isopentenyl units).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction
- geranyl diphosphate + 7 isopentenyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] 7 diphosphate + all-trans-nonaprenyl diphosphate
This enzyme is involved in the synthesis of the side chain of menaquinone-9.
References
- ↑ "Solanesyl pyrophosphate synthetase from Micrococcus lysodeikticus". Biochemistry 16 (21): 4616–22. October 1977. doi:10.1021/bi00640a014. PMID 911777.
- ↑ "Variable product specificity of solanesyl pyrophosphate synthetase". Biochemical and Biophysical Research Communications 96 (4): 1648–53. October 1980. doi:10.1016/0006-291X(80)91363-7. PMID 7447947.
- ↑ "Two solanesyl diphosphate synthases with different subcellular localizations and their respective physiological roles in Oryza sativa". Journal of Experimental Botany 61 (10): 2683–92. June 2010. doi:10.1093/jxb/erq103. PMID 20421194.
- ↑ "Purification of solanesyl-diphosphate synthase from Micrococcus luteus. A new class of prenyltransferase". The Journal of Biological Chemistry 266 (35): 23706–13. December 1991. PMID 1748647.
- ↑ "Farnesyl diphosphate synthase and solanesyl diphosphate synthase reactions of diphosphate-modified allylic analogs: the significance of the diphosphate linkage involved in the allylic substrates for prenyltransferase". Journal of Biochemistry 112 (1): 20–7. July 1992. PMID 1429508.
- ↑ "Biosynthesis of the side chain of ubiquinone:trans-prenyltransferase in rat liver microsomes". The Journal of Biological Chemistry 268 (31): 23081–6. November 1993. PMID 8226825.
External links
- All-trans-nonaprenyl-diphosphate+synthase+(geranyl-diphosphate+specific) at the US National Library of Medicine Medical Subject Headings (MeSH)
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