Biology:Long-chain-enoyl-CoA hydratase
From HandWiki
| long-chain-enoyl-CoA hydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.1.74 | ||||||||
| CAS number | 62009-81-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme long-chain-enoyl-CoA hydratase (EC 4.2.1.74) catalyzes the chemical reaction
- (3S)-3-hydroxyacyl-CoA [math]\displaystyle{ \rightleftharpoons }[/math] trans-2-enoyl-CoA + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase. This enzyme is also called long-chain enoyl coenzyme A hydratase. This enzyme participates in fatty acid elongation in mitochondria and fatty acid metabolism.
References
- "Purification and properties of pig heart crotonase and the presence of short chain and long chain enoyl coenzyme A hydratases in pig and guinea pig tissues". J. Biol. Chem. 252 (2): 542–7. 1977. PMID 833142.
- Schulz H (1974). "Long chain enoyl coenzyme A hydratase from pig heart". J. Biol. Chem. 249 (9): 2704–9. PMID 4828315.
 |  |
