Biology:2-dehydro-3-deoxy-L-pentonate aldolase
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Short description: Class of enzymes
| 2-dehydro-3-deoxy-L-pentonate aldolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.2.18 | ||||||||
| CAS number | 9076-49-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme 2-dehydro-3-deoxy-L-pentonate aldolase (EC 4.1.2.18) catalyzes the chemical reaction
- 2-dehydro-3-deoxy-L-pentonate [math]\displaystyle{ \rightleftharpoons }[/math] pyruvate + glycolaldehyde
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxy-L-pentonate aldolase, 2-keto-3-deoxy-L-arabonate aldolase, 2-keto-3-deoxy-D-xylonate aldolase, 3-deoxy-D-pentulosonic acid aldolase, and 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase. This enzyme participates in fructose and mannose metabolism.
References
- "2-keto-3-deoxyl-L-arabonate aldolase and its role in a new pathway of L-arabinose degradation". Biochem. Biophys. Res. Commun. 36 (5): 809–14. 1969. doi:10.1016/0006-291X(69)90681-0. PMID 5808295.
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