Biology:3-hydroxypropionyl-CoA synthase

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Short description: Class of enzymes
3-Hydroxypropionyl-CoA synthase
Identifiers
EC number6.2.1.36
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

3-Hydroxypropionyl-CoA synthase (EC 6.2.1.36, 3-hydroxypropionyl-CoA synthetase (AMP-forming), 3-hydroxypropionate-CoA ligase) is an enzyme with systematic name hydroxypropionate:CoA ligase (AMP-forming).[1][2] This enzyme catalyses the following chemical reaction

3-hydroxypropionate + ATP + CoA [math]\displaystyle{ \rightleftharpoons }[/math] 3-hydroxypropionyl-CoA + AMP + diphosphate

This enzyme catalyses a step in the 3-hydroxypropionate/4-hydroxybutyrate cycle.

References

  1. "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea". Science 318 (5857): 1782–6. December 2007. doi:10.1126/science.1149976. PMID 18079405. 
  2. "3-Hydroxypropionyl-coenzyme A synthetase from Metallosphaera sedula, an enzyme involved in autotrophic CO2 fixation". Journal of Bacteriology 190 (4): 1383–9. February 2008. doi:10.1128/JB.01593-07. PMID 18165310. 

External links