Biology:Trans-resveratrol di-O-methyltransferase
From HandWiki
| Trans-resveratrol di-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.240 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Trans-resveratrol di-O-methyltransferase (EC 2.1.1.240, ROMT, resveratrol O-methyltransferase, pterostilbene synthase) is an enzyme with systematic name S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase.[1] This enzyme catalyses the following chemical reaction
- 2 S-adenosyl-L-methionine + trans-resveratrol [math]\displaystyle{ \rightleftharpoons }[/math] 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction)
- (1a) S-adenosyl-L-methionine + trans-resveratrol [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene
- (1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + pterostilbene
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
References
- ↑ "A stress-inducible resveratrol O-methyltransferase involved in the biosynthesis of pterostilbene in grapevine". Plant Physiology 148 (3): 1630–9. November 2008. doi:10.1104/pp.108.126003. PMID 18799660.
External links
- Trans-resveratrol+di-O-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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