Biology:24-methylenesterol C-methyltransferase
From HandWiki
Short description: Class of enzymes
| 24-methylenesterol C-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.143 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 24-methylenesterol C-methyltransferase (EC 2.1.1.143) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + 24-methylenelophenol [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + (Z)-24-ethylidenelophenol
Thus, the two substrates of this enzyme are S-adenosyl methionine and 24-Methylenelophenol, whereas its two products are S-adenosylhomocysteine and (Z)-24-ethylidenelophenol.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase. Other names in common use include SMT2, and 24-methylenelophenol C-241-methyltransferase. This enzyme participates in the biosynthesis of steroids.
References
- "Two families of sterol methyltransferases are involved in the first and the second methylation steps of plant sterol biosynthesis". Eur. J. Biochem. 256 (1): 88–96. 1998. doi:10.1046/j.1432-1327.1998.2560088.x. PMID 9746350.
 |  |
