Biology:Propionate CoA-transferase
From HandWiki
Short description: Class of enzymes
| propionate CoA-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.8.3.1 | ||||||||
| CAS number | 9026-15-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a propionate CoA-transferase (EC 2.8.3.1) is an enzyme that catalyzes the chemical reaction
- acetyl-CoA + propanoate [math]\displaystyle{ \rightleftharpoons }[/math] acetate + propanoyl-CoA
Thus, the two substrates of this enzyme are acetyl-CoA and propanoate, whereas its two products are acetate and propanoyl-CoA.
This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is acetyl-CoA:propanoate CoA-transferase. Other names in common use include propionate coenzyme A-transferase, propionate-CoA:lactoyl-CoA transferase, propionyl CoA:acetate CoA transferase, and propionyl-CoA transferase. This enzyme participates in 3 metabolic pathways: pyruvate metabolism, propanoate metabolism, and styrene degradation.
References
- "Acyl-coenzyme A synthesis by phosphotransacetylase and coenzyme A transphorase". Fed. Proc. 11: 291. 1952.
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