Biology:Alcohol sulfotransferase
From HandWiki
Short description: Class of enzymes
| Alcohol sulfotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.8.2.2 | ||||||||
| CAS number | 9032-76-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Alcohol sulfotransferase is an enzyme that catalyzes the sulfate conjugation of primary and secondary alcohols including many hormones, neurotransmitters, drugs, and xenobiotic compounds.[1][2]
The chemical reaction is:
an alcohol + 3'-phosphoadenylyl-sulfate adenosine 3',5'-bisphosphate + an organosulfate + H+
Family members
Human genes that encode alcohol sulfotransferases include:
See also
References
- ↑ "The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases". Arch. Biochem. Biophys. 202 (2): 474–81. July 1980. doi:10.1016/0003-9861(80)90452-X. PMID 6935986.
- ↑ "Hydroxysteroid sulfotransferase". Detoxication and Drug Metabolism: Conjugation and Related Systems. Meth. Enzymol.. 77. 1981. pp. 206–13. doi:10.1016/S0076-6879(81)77027-7. ISBN 978-0-12-181977-4.
External links
- alcohol+sulfotransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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