Biology:Trans-o-hydroxybenzylidenepyruvate hydratase-aldolase
From HandWiki
| trans-o-Hydroxybenzylidenepyruvate hydratase-aldolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.2.45 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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trans-o-Hydroxybenzylidenepyruvate hydratase-aldolase (EC 4.1.2.45, 2′-hydroxybenzalpyruvate aldolase, NsaE, tHBPA hydratase-aldolase) is an enzyme with systematic name (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate hydro-lyase.[1][2][3][4] This enzyme catalyses the following chemical reaction
- (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] salicylaldehyde + pyruvate
This enzyme is involved in naphthalene degradation.
References
- ↑ "Purification and properties of 2'-hydroxybenzalpyruvate aldolase from a bacterium that degrades naphthalenesulfonates". The Journal of Biological Chemistry 268 (13): 9484–9. May 1993. PMID 8486638.
- ↑ "Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6". Microbiology 152 (Pt 7): 1929–40. July 2006. doi:10.1099/mic.0.28783-0. PMID 16804169.
- ↑ "Organization and evolution of naphthalene catabolic pathways: sequence of the DNA encoding 2-hydroxychromene-2-carboxylate isomerase and trans-o-hydroxybenzylidenepyruvate hydratase-aldolase from the NAH7 plasmid". Journal of Bacteriology 176 (24): 7757–62. December 1994. doi:10.1128/jb.176.24.7757-7762.1994. PMID 8002605.
- ↑ "trans-o-Hydroxybenzylidenepyruvate hydratase-aldolase as a biocatalyst". Applied and Environmental Microbiology 66 (6): 2668–72. June 2000. doi:10.1128/aem.66.6.2668-2672.2000. PMID 10831455.
External links
- Trans-o-hydroxybenzylidenepyruvate+hydratase-aldolase at the US National Library of Medicine Medical Subject Headings (MeSH)
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