Biology:UDP-glucose 4,6-dehydratase
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Short description: Class of enzymes
UDP-glucose 4,6-dehydratase | |||||||||
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Identifiers | |||||||||
EC number | 4.2.1.76 | ||||||||
CAS number | 68189-53-7 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme UDP-glucose 4,6-dehydratase (EC 4.2.1.76) catalyzes the chemical reaction
- UDP-glucose [math]\displaystyle{ \rightleftharpoons }[/math] UDP-4-dehydro-6-deoxy-D-glucose + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming). Other names in common use include UDP-D-glucose-4,6-hydrolyase, UDP-D-glucose oxidoreductase, and UDP-glucose 4,6-hydro-lyase. This enzyme participates in nucleotide sugars metabolism.
References
- "The formation of UDP-L-rhamnose from UDP-D-glucose by an enzyme preparation of red campion (Silene dioica (L) Clairv) leaves". FEBS Lett. 91 (2): 281–4. 1978. doi:10.1016/0014-5793(78)81192-2. PMID 680134.
Original source: https://en.wikipedia.org/wiki/UDP-glucose 4,6-dehydratase.
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