Biology:Choline sulfotransferase

From HandWiki
Revision as of 22:15, 15 February 2024 by CodeMe (talk | contribs) (change)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Short description: Class of enzymes
choline sulfotransferase
Identifiers
EC number2.8.2.6
CAS number9047-23-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a choline sulfotransferase (EC 2.8.2.6) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + choline [math]\displaystyle{ \rightleftharpoons }[/math] adenosine 3',5'-bisphosphate + choline sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and choline, whereas its two products are adenosine 3',5'-bisphosphate and choline sulfate.[1]

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:choline sulfotransferase. This enzyme is also called choline sulphokinase. This enzyme participates in sulfur metabolism.

References

  1. "Choline sulphokinase (sulphotransferase)". J. (Tokyo) Biochem.: 81–91. [need quotation to verify]