Biology:Artemisinic aldehyde Delta11(13)-reductase
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Short description: Class of enzymes
| Artemisinic aldehyde Delta11(13)-reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.1.92 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Artemisinic aldehyde Delta11(13)-reductase (EC 1.3.1.92, Dbr2) is an enzyme with systematic name artemisinic aldehyde:NADP+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
- (11R)-dihydroartemisinic aldehyde + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] artemisinic aldehyde + NADPH + H+
This enzyme i present in Artemisia annua.
References
- ↑ "Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua". Planta Medica 71 (1): 40–7. January 2005. doi:10.1055/s-2005-837749. PMID 15678372.
- ↑ "The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua". The Journal of Biological Chemistry 283 (31): 21501–8. August 2008. doi:10.1074/jbc.M803090200. PMID 18495659.
External links
- Artemisinic+aldehyde+Delta11(13)-reductase at the US National Library of Medicine Medical Subject Headings (MeSH)
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