Biology:(+)-Pulegone reductase

From HandWiki
Short description: Class of enzymes
(+)-pulegone reductase
Identifiers
EC number1.3.1.81
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

(+)-pulegone reductase (EC 1.3.1.81) is an enzyme with systematic name (−)-menthone:NADP+ oxidoreductase.[1] This enzyme catalises the following chemical reaction

(1) (−)-menthone + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] (+)-pulegone + NADPH + H+
(2) (+)-isomenthone + NADP+ [math]\displaystyle{ \rightleftharpoons }[/math] (+)-pulegone + NADPH + H+

NADH cannot replace NADPH as reductant.

References

  1. "Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint". Archives of Biochemistry and Biophysics 418 (1): 80–92. October 2003. doi:10.1016/s0003-9861(03)00390-4. PMID 13679086. 

External links