Biology:(+)-sativene synthase
From HandWiki
Short description: Class of enzymes
| (+)-sativene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.129 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
(+)-Sativene synthase (EC 4.2.3.129, cop4) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-sativene-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate [math]\displaystyle{ \rightleftharpoons }[/math] (+)-sativene + diphosphate
This enzyme is isolated from the fungus Coprinus cinereus.
References
- ↑ "Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus". Molecular Microbiology 72 (5): 1181–95. June 2009. doi:10.1111/j.1365-2958.2009.06717.x. PMID 19400802.
- ↑ "Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers". ChemBioChem 11 (8): 1093–106. May 2010. doi:10.1002/cbic.200900671. PMID 20419721.
- ↑ "Selectivity of fungal sesquiterpene synthases: role of the active site's H-1α loop in catalysis". Applied and Environmental Microbiology 76 (23): 7723–33. December 2010. doi:10.1128/aem.01811-10. PMID 20889795. Bibcode: 2010ApEnM..76.7723L.
External links
- (+)-sativene+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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