Biology:(-)-endo-fenchol synthase
From HandWiki
| (−)-endo-fenchol synthase | |||||||||
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| Identifiers | |||||||||
| EC number | 4.2.3.10 | ||||||||
| CAS number | 117758-41-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme (–)-endo-Fenchol synthase (EC 4.2.3.10) catalyzes the chemical reaction
- geranyl diphosphate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] (–)-endo-fenchol + diphosphate
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranyl-diphosphate diphosphate-lyase [cyclizing, (–)-endo-fenchol-forming]. Other names in common use include (−)-endo-fenchol cyclase, and geranyl pyrophosphate:(−)-endo-fenchol cyclase. This enzyme participates in monoterpenoid biosynthesis.
References
- "Monoterpene biosynthesis: mechanistic evaluation of the geranyl pyrophosphate:(−)-endo-fenchol cyclase from fennel (Foeniculum vulgare)". Arch. Biochem. Biophys. 269 (2): 507–16. 1989. doi:10.1016/0003-9861(89)90134-3. PMID 2919880.
- "Biosynthesis of monoterpenes. Stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (−)-endo-fenchol". J. Biol. Chem. 263 (30): 15449–53. 1988. doi:10.1016/S0021-9258(19)37609-4. PMID 3170591.
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