Biology:16S rRNA (cytosine967-C5)-methyltransferase
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Short description: Class of enzymes
| 16S rRNA (cytosine967-C5)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.176 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
16S rRNA (cytosine967-C5)-methyltransferase (EC 2.1.1.176, rsmB (gene), fmu (gene), 16S rRNA m5C967 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (cytosine967-C5)-methyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + cytosine967 in 16S rRNA [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + 5-methylcytosine967 in 16S rRNA
The enzyme specifically methylates cytosine967 at C5 in 16S rRNA.
References
- ↑ "Purification, cloning, and characterization of the 16S RNA m5C967 methyltransferase from Escherichia coli". Biochemistry 38 (6): 1884–92. February 1999. doi:10.1021/bi981880l. PMID 10026269.
- ↑ "Identification of the 16S rRNA m5C967 methyltransferase from Escherichia coli". Biochemistry 38 (13): 4053–7. March 1999. doi:10.1021/bi982364y. PMID 10194318.
- ↑ "The first structure of an RNA m5C methyltransferase, Fmu, provides insight into catalytic mechanism and specific binding of RNA substrate". Structure 11 (12): 1609–20. December 2003. doi:10.1016/j.str.2003.10.014. PMID 14656444.
External links
- 16S+rRNA+(cytosine967-C5)-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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