Biology:2-hydroxyethylphosphonate dioxygenase
From HandWiki
Short description: Class of enzymes
| 2-hydroxyethylphosphonate dioxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.13.11.72 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
2-hydroxyethylphosphonate dioxygenase (EC 1.13.11.72, HEPD, phpD (gene)) is an enzyme with systematic name 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (hydroxymethylphosphonate forming).[1][2] This enzyme catalyses the following chemical reaction
- REDIRECT Template:Chemical reaction
2-hydroxyethylphosphonate dioxygenase contains non-heme-Fe(II) and is involved in the biosynthesis of phosphinothricin.[3][4]
References
- ↑ "On the stereochemistry of 2-hydroxyethylphosphonate dioxygenase". Journal of the American Chemical Society 133 (12): 4236–9. March 2011. doi:10.1021/ja1113326. PMID 21381767. Bibcode: 2011JAChS.133.4236W.
- ↑ "Mechanism and substrate recognition of 2-hydroxyethylphosphonate dioxygenase". Biochemistry 50 (30): 6598–605. August 2011. doi:10.1021/bi200804r. PMID 21711001.
- ↑ Enzyme 1.13.11.72 at KEGG Pathway Database.
- ↑ "An unusual carbon-carbon bond cleavage reaction during phosphinothricin biosynthesis". Nature 459 (7248): 871–4. June 2009. doi:10.1038/nature07972. PMID 19516340. Bibcode: 2009Natur.459..871C.
External links
- 2-hydroxyethylphosphonate+dioxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)
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