Biology:2-methylisoborneol synthase
From HandWiki
Short description: Class of enzymes
| 2-methylisoborneol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.118 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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2-methylisoborneol synthase (EC 4.2.3.118, sco7700, 2-MIB cyclase, MIB synthase, MIBS) is an enzyme with systematic name (E)-2-methylgeranyl-diphosphate diphosphate-lyase (cyclizing, 2-methylisoborneol-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- (E)-2-methylgeranyl diphosphate + H2O [math]\displaystyle{ \rightleftharpoons }[/math] 2-methylisoborneol + diphosphate
The product, 2-methylisoborneol, is a characteristic odiferous compound with a musty smell produced by soil microorganisms.
References
- ↑ "Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor". Journal of the American Chemical Society 130 (28): 8908–9. July 2008. doi:10.1021/ja803639g. PMID 18563898.
- ↑ "Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol". Proceedings of the National Academy of Sciences of the United States of America 105 (21): 7422–7. May 2008. doi:10.1073/pnas.0802312105. PMID 18492804. Bibcode: 2008PNAS..105.7422K.
- ↑ "Biosynthesis of 2-methylisoborneol in cyanobacteria". Environmental Science & Technology 45 (3): 992–8. February 2011. doi:10.1021/es102992p. PMID 21174459. Bibcode: 2011EnST...45..992G.
External links
- 2-methylisoborneol+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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