Biology:23S rRNA (guanosine2251-2'-O)-methyltransferase
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Short description: Class of enzymes
| 23S rRNA (guanosine2251-2'-O)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.185 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
23S rRNA (guanosine2251-2'-O)-methyltransferase (EC 2.1.1.185, rlmB (gene), yifH (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanosine2251-2'-O-)-methyltransferase.[1][2] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + guanosine2251 in 23S rRNA [math]\displaystyle{ \rightleftharpoons }[/math] S-adenosyl-L-homocysteine + 2'-O-methylguanosine2251 in 23S rRNA
The enzyme catalyses the methylation of guanosine2251.
References
- ↑ "The rlmB gene is essential for formation of Gm2251 in 23S rRNA but not for ribosome maturation in Escherichia coli". Journal of Bacteriology 183 (23): 6957–60. December 2001. doi:10.1128/jb.183.23.6957-6960.2001. PMID 11698387.
- ↑ "The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot". Structure 10 (10): 1303–15. October 2002. doi:10.1016/s0969-2126(02)00852-3. PMID 12377117.
External links
- 23S+rRNA+(guanosine2251-2'-O)-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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