Biology:3-deoxy-D-manno-octulosonate aldolase
From HandWiki
Short description: Class of enzymes
| 3-deoxy-D-manno-octulosonate aldolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.2.23 | ||||||||
| CAS number | 9026-95-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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The enzyme 3-deoxy-D-manno-octulosonate aldolase (EC 4.1.2.23) catalyzes the chemical reaction
- 3-deoxy-D-manno-octulosonate [math]\displaystyle{ \rightleftharpoons }[/math] pyruvate + D-arabinose
This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxyoctonate aldolase, KDOaldolase, 3-deoxyoctulosonic aldolase, 2-keto-3-deoxyoctonic aldolase, 3-deoxy-D-manno-octulosonic aldolase, and 3-deoxy-D-manno-octulosonate D-arabinose-lyase.
References
- "The biosynthesis of cell wall lipopolysaccharide in Escherichia coli. V. Purification and properties of 3-deoxy-D-manno-octulosonate aldolase". J. Biol. Chem. 241 (13): 3222–7. 1966. PMID 5912115.
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