Biology:3-hydroxyanthranilate 4-C-methyltransferase
| 3-hydroxyanthranilate 4-C-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.97 | ||||||||
| CAS number | 112445-22-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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3-hydroxyanthranilate 4-C-methyltransferase (EC 2.1.1.97) is an enzyme that catalyzes the chemical reaction
- REDIRECT Template:Chemical reaction
This is a methylation reaction in which the 3-hydroxyanthranilic acid, is converted to 3-hydroxy-4-methylanthranilic acid. The methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH).[1]
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase. This enzyme is also called 3-hydroxyanthranilate 4-methyltransferase. The reaction is part of the biosynthetic pathway to actinomycin in Streptomyces antibioticus[2]
References
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